⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907466 | 0.75 | — | — | |
| SCHEMBL654920 | 0.75 | — | — | |
| SCHEMBL640472 | 0.75 | — | — | |
| SCHEMBL5661526 | 0.75 | — | — | |
| SCHEMBL6154889 | 0.75 | — | — | |
| SCHEMBL1805666 | 0.75 | — | — | |
| SCHEMBL6650319 | 0.69 | TRPV4 (0.63) | — | |
| SCHEMBL5847131 | 0.69 | IDO1 (0.42) | — | |
| SCHEMBL9374081 | 0.69 | IDO1 (0.47) | — | |
| SCHEMBL364114 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116019794-A | Application of amino fullerene material in preparation of exosome PD-L1 inhibition drugs | 中国科学院化学研究所 | 2023-04-28 | — | — | CN | claimed |
| CN-114105972-B | Cinchonine derivative and application thereof in preparation of high-optical-purity indoxacarb intermediate | 安徽广信农化股份有限公司 | 2022-12-23 | — | — | CN | claimed |
| EP-4021441-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | Trustees of Dartmouth College (US) | 2022-07-06 | — | — | EP | claimed |
| CN-114105972-A | Xinkening derivative and application thereof in preparation of high-optical-purity indoxacarb intermediate | 安徽广信农化股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| WO-2021042046-A1 | MEMBRANE-ACTIVE ANTI-BACTERIAL COMPOUNDS AND USES THEREOF | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2021-03-04 | — | — | WO | claimed |
| CN-111196783-A | 2,4, 6-substituted pyrimidine derivatives containing acyl urea structure, and preparation method and application thereof | 郑州大学 | 2020-05-26 | — | — | CN | claimed |
| CN-106380465-A | 1,2,3-Triazole structure unit-containing 2,4-disubstituted quinazoline compounds, and preparation method and use thereof | 郑州大学 | 2017-02-08 | — | — | CN | claimed |
| EP-0748219-B8 | COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS | SUGEN INC (US) | 2005-06-08 | — | — | EP | claimed |
| EP-0748219-B1 | COMPOUNDS FOR THE TREATMENT OF DISORDERS RELATED TO VASCULOGENESIS AND/OR ANGIOGENESIS | SUGEN INC (US) | 2005-04-06 | — | — | EP | claimed |
| EP-1075261-A1 | MYCOBACTERIAL INHIBITORS | AstraZeneca AB (SE) | 2001-02-14 | — | — | EP | claimed |
| EP-0439265-B1 | Novel 1,3-dicarbonyl compounds and their use | PFIZER (US) | 1994-03-23 | — | — | EP | claimed |
| US-5238909-A | For preemergence or postemergence use | EASTMAN KODAK COMPANY (US) | 1993-08-24 | — | — | US | claimed |
| US-5176717-A | USE OF SULFONATED POLYAZO DYES FOR DYEING LEATHER IN BRILLIANT FAST RED SHADES | CIBA-GEIGY CORPORATION (US) | 1993-01-05 | — | — | US | claimed |
| US-5166161-A | Antiallergens or antiinflammatory agents | PFIZER INC. (US) | 1992-11-24 | — | — | US | claimed |
| EP-0476761-A1 | 4-substituted isoxazoles | EASTMAN KODAK COMPANY (US) | 1992-03-25 | — | — | EP | claimed |
| EP-0476760-A2 | 4-substituted isoxazole herbicides | EASTMAN KODAK COMPANY (US) | 1992-03-25 | — | — | EP | claimed |
| EP-0468922-A2 | Use of polyazodyes for dyeing leather | CIBA-GEIGY AG (CH) | 1992-01-29 | — | — | EP | claimed |
| EP-0439265-A1 | Novel 1,3-dicarbonyl compounds and their use | PFIZER INC. (US) | 1991-07-31 | — | — | EP | claimed |
| US-4425270-A | Reactive disazo compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-01-10 | — | — | US | claimed |
| EP-0087709-A1 | N,N',N\"-triaryl-1,2,3-triaminopropane derivatives, process for their preparation and their use as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-07 | — | — | EP | claimed |