Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817092 | 0.82 | EGLN1 (0.43) | EGLN1KDM4ENPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1810830 | 0.81 | EGLN1 (0.46) | EGLN1KDM4EL3MBTL1SMN1; SMN2ERCC1 | |
| SCHEMBL1808866 | 0.81 | EGLN1 (0.71) | EGLN1 | |
| SCHEMBL1809791 | 0.78 | TP53 (0.47) | EGLN1KDM4EKMT2ANPSR1CYP1A2 | |
| SCHEMBL3239918 | 0.76 | KDM4E (0.51) | KDM4EKMT2ATDP1GAAMAPT | |
| SCHEMBL1811763 | 0.74 | EGLN1 (0.43) | EGLN1KDM4EKMT2ANPSR1GAA | |
| SCHEMBL15931650 | 0.73 | KDM4E (0.62) | KDM4EKMT2ANPSR1CYP1A2CYP2C9 | |
| SCHEMBL1270134 | 0.72 | EGLN1 (0.62) | EGLN1KDM4EKMT2ACYP1A2CYP2C9 | |
| SCHEMBL4134050 | 0.72 | TP53 (0.64) | KDM4EKMT2ANPSR1CYP1A2CYP2C9 | |
| SCHEMBL2017928 | 0.71 | EGLN1 (0.58) | EGLN1KDM4ENPSR1GAAERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |