Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900111 | 0.86 | OPRK1 (0.68) | OPRK1KMT2AMEN1 | |
| SCHEMBL3972087 | 0.85 | OPRK1 (0.52) | OPRK1KMT2AMEN1RAB9AEPHX2 | |
| SCHEMBL5799392 | 0.83 | KAT6A (0.54) | OPRK1KMT2AMEN1RAB9AEPHX2 | |
| SCHEMBL3967321 | 0.83 | KAT6A (0.51) | OPRK1KMT2AMEN1RAB9AEPHX2 | |
| SCHEMBL3292130 | 0.82 | OPRK1 (0.49) | OPRK1KMT2AMEN1EPHX2HRH1 | |
| SCHEMBL19610260 | 0.82 | CHRM3 (0.53) | OPRK1KMT2AMEN1EPHX2 | |
| SCHEMBL5271411 | 0.81 | EPHX2 (0.59) | EPHX2HRH1 | |
| SCHEMBL2932615 | 0.81 | EPHX2 (0.63) | OPRK1EPHX2HRH1CCR3 | |
| SCHEMBL15637209 | 0.81 | SLC6A2 (0.50) | OPRK1KMT2AMEN1EPHX2GAA | |
| SCHEMBL3605088 | 0.80 | EPHX2 (0.59) | EPHX2HRH1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051296-B2 | Aryl carboxamide derivatives as TTX-S blockers | RAQUALIA PHARMA INC. (JP) | 2015-06-09 | — | — | US | disclosed |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-09-13 | — | — | US | disclosed |
| WO-2011058766-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | SCN1B, SCN1A, SCN2B | OPRK1 157/4885KMT2A 1032/4885MEN1 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.