Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18079659 | 1.00 | FFAR4 (0.38) | FFAR4BRD4PDE4APDE4BPDE4C | |
| SCHEMBL15134548 | 0.87 | LOX (0.40) | FFAR4BRD4LOXLOXL2MCHR1 | |
| SCHEMBL15134547 | 0.87 | LOX (0.40) | FFAR4BRD4LOXLOXL2MCHR1 | |
| SCHEMBL18079661 | 0.82 | CNR2 (0.41) | MCHR1 | |
| SCHEMBL15215038 | 0.82 | CNR2 (0.41) | MCHR1 | |
| SCHEMBL15215050 | 0.82 | CNR2 (0.41) | MCHR1 | |
| SCHEMBL15128995 | 0.81 | FFAR4 (0.37) | FFAR4BRD4PDE4APDE4BPDE4C | |
| SCHEMBL15128994 | 0.81 | FFAR4 (0.37) | FFAR4BRD4PDE4APDE4BPDE4C | |
| SCHEMBL15129000 | 0.81 | FFAR4 (0.37) | FFAR4BRD4PDE4APDE4BPDE4C | |
| SCHEMBL18079658 | 0.81 | CNR2 (0.40) | FFAR4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447078-B2 | Substituted heterocyclic compounds for disease treatment | ACUCELA INC. (US) | 2016-09-20 | — | — | US | disclosed |