Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15215038 | 1.00 | CNR2 (0.41) | CNR2CCNA2CDK2CCNA1MCHR1 | |
| SCHEMBL15215050 | 1.00 | CNR2 (0.41) | CNR2CCNA2CDK2CCNA1MCHR1 | |
| SCHEMBL18079658 | 0.99 | CNR2 (0.40) | CNR2CCNA2CDK2CCNA1MCHR1 | |
| SCHEMBL15134558 | 0.88 | CNR2 (0.41) | CNR2CCNA2CDK2CCNA1MCHR1 | |
| SCHEMBL15134570 | 0.88 | CNR2 (0.41) | CNR2CCNA2CDK2CCNA1MCHR1 | |
| SCHEMBL15129091 | 0.88 | CNR2 (0.41) | CNR2CCNA2CDK2CCNA1MCHR1 | |
| SCHEMBL15134551 | 0.86 | CNR2 (0.40) | CNR2CCNA2CDK2CCNA1MCHR1 | |
| SCHEMBL18079652 | 0.82 | FFAR4 (0.38) | MCHR1 | |
| SCHEMBL18079659 | 0.82 | FFAR4 (0.38) | MCHR1 | |
| SCHEMBL15128996 | 0.81 | CNR2 (0.41) | CNR2CCNA2CDK2CCNA1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447078-B2 | Substituted heterocyclic compounds for disease treatment | ACUCELA INC. (US) | 2016-09-20 | — | — | US | disclosed |