Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 19/20 | 0.60 |
| ▸ | ARG2 | P78540 | 15/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10006126 | 1.00 | ARG1 (0.60) | ARG1ARG2 | |
| SCHEMBL10006127 | 1.00 | ARG1 (0.60) | ARG1ARG2 | |
| SCHEMBL18079738 | 0.89 | ARG1 (0.64) | ARG1ARG2 | |
| SCHEMBL10006201 | 0.89 | ARG1 (0.64) | ARG1ARG2 | |
| SCHEMBL10006203 | 0.89 | ARG1 (0.64) | ARG1ARG2 | |
| SCHEMBL18079497 | 0.88 | ARG1 (0.63) | ARG1ARG2 | |
| SCHEMBL10006079 | 0.85 | ARG1 (0.66) | ARG1ARG2 | |
| SCHEMBL10006080 | 0.85 | ARG1 (0.66) | ARG1ARG2 | |
| SCHEMBL10006051 | 0.80 | ARG1 (0.65) | ARG1ARG2 | |
| SCHEMBL10006050 | 0.80 | ARG1 (0.65) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447122-B2 | Arginase inhibitors and methods of use thereof | ASTRAZENECA AB (SE) | 2016-09-20 | — | — | US | disclosed |