Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 17/20 | 0.55 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 5/20 | 0.53 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18080297 | 0.92 | P2RY2 (0.53) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18080280 | 0.89 | P2RY2 (0.57) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18080281 | 0.88 | P2RY2 (0.59) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18080296 | 0.85 | P2RY2 (0.54) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18080289 | 0.84 | P2RY2 (0.55) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18080315 | 0.84 | P2RY2 (0.58) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18080308 | 0.83 | P2RY2 (0.59) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18080320 | 0.83 | P2RY2 (0.59) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18080282 | 0.83 | P2RY2 (0.56) | P2RY2P2RY4P2RY6 | |
| SCHEMBL18080273 | 0.82 | P2RY2 (0.60) | P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | P2RY2 980/4885P2RY4 709/4885P2RY6 808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.