Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18080448 | 0.83 | TRPV1 (0.33) | TRPV1RPS6KA3EIF4A3 | |
| SCHEMBL18080484 | 0.83 | DCUN1D1 (0.32) | DCUN1D1 | |
| SCHEMBL16631415 | 0.80 | DCUN1D1 (0.33) | DCUN1D1RPS6KA3 | |
| SCHEMBL18080492 | 0.79 | — | — | |
| SCHEMBL18080490 | 0.78 | — | — | |
| SCHEMBL18080495 | 0.77 | EIF4A3 (0.33) | TRPV1EIF4A3 | |
| SCHEMBL18080503 | 0.76 | EIF4A3 (0.33) | TRPV1EIF4A3 | |
| SCHEMBL18080488 | 0.75 | — | — | |
| SCHEMBL18080513 | 0.72 | KDM4E (0.32) | EIF4A3 | |
| SCHEMBL18080481 | 0.72 | NR1I3 (0.35) | DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | DCUN1D1 580/4885TRPV1 3709/4885RPS6KA3 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.