Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312472 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL30349823 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL11203642 | 0.64 | ALDH1A1 (0.30) | — | |
| SCHEMBL15003547 | 0.64 | — | — | |
| SCHEMBL15711352 | 0.64 | — | — | |
| SCHEMBL18434778 | 0.64 | — | — | |
| SCHEMBL20977414 | 0.64 | — | — | |
| SCHEMBL30349850 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL19308518 | 0.64 | — | — | |
| SCHEMBL24488665 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924565-B1 | DIAMINOPYRIMIDINES AS P2X3 AND P3X2/3 MODULATORS | HOFFMANN LA ROCHE (CH) | 2016-09-14 | — | — | EP | disclosed |