Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15250406 | 0.79 | MAPT (0.39) | MAPT | |
| SCHEMBL16378173 | 0.79 | MAPT (0.39) | MAPT | |
| SCHEMBL15250123 | 0.78 | NAAA (0.35) | MAPT | |
| SCHEMBL15671759 | 0.76 | MAPT (0.48) | MAPTTP53POLBHPGDGAA | |
| SCHEMBL17523462 | 0.75 | MAPT (0.36) | MAPT | |
| SCHEMBL15250127 | 0.75 | MAPT (0.33) | MAPT | |
| SCHEMBL16918696 | 0.74 | MAPT (0.45) | MAPTTP53POLBHPGDGAA | |
| SCHEMBL18307208 | 0.73 | MAPT (0.36) | MAPT | |
| SCHEMBL16588496 | 0.72 | CHRM2 (0.31) | — | |
| SCHEMBL15752236 | 0.71 | MAPT (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067405-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2016-09-14 | — | — | EP | disclosed |