SCHEMBL1808230

SCHEMBL1808230

NNC(=O)c1c[nH]nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4758620 0.81
SCHEMBL1249452 0.79
SCHEMBL30163145 0.79 MEN1 (0.39)
SCHEMBL9957276 0.79 CNR1 (0.38)
SCHEMBL19119308 0.77
SCHEMBL27062540 0.76 NPC1 (0.42)
SCHEMBL30522334 0.76
SCHEMBL44757 0.76
SCHEMBL8314948 0.75
SCHEMBL3896577 0.75 CES2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115490644-B 1,2, 3-Triazole-4-hydrazide Schiff base fluorescent probe and preparation method and application thereof 海南师范大学 2024-09-24 CN claimed
CN-113661999-A Compound of triazole hydrazide compound and azole bactericide and application thereof 南京农业大学 2021-11-19 CN claimed
CN-104926738-B Application of 1,2,3-triazole-4-hydrazide derivatives to preparation of agricultural bactericide 南京农业大学 2017-05-24 CN claimed
CN-104926738-A Application of 1,2,3-triazole-4-hydrazide derivatives to preparation of agricultural bactericide UNIV NANJING AGRICULTURAL 2015-09-23 CN claimed
US-8835442-B2 3-substituted 7-imino-2-thioxo-3, 7-dihydro-2H-thiazolo [4,5-di pyrimidin-6-yl—and process for preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-09-16 US claimed
EP-2501706-B1 A NOVEL 3-SUBSTITUTED 7-IMINO-2-THIOXO-3, 7-DIHYDRO-2H-THIAZOLO [4,5-DI PYRIMIDIN-6-YL - AND PROCESS FOR PREPARATION THEREOF COUNCIL SCIENT IND RES (IN) 2014-08-06 EP claimed
WO-2011061754-A9 A NOVEL 3-SUBSTITUTED 7-IMINO-2-THIOXO-3, 7-DIHYDRO-2H-THIAZOLO [4,5-DI PYRIMIDIN-6-YL - AND PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-07-05 WO claimed
EP-0425283-B1 Novel triazolyl hydrazide derivatives and process for their preparation EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1995-05-10 EP claimed
US-5225410-A Antiangina, antiulcer agents EGIS GYOGYSZERGYAR (HU) 1993-07-06 US claimed
CN-1051173-A new triazolyl hydrazide derivative and preparation method thereof EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1991-05-08 CN claimed
EP-0425282-A2 Triazolo derivatives and process for their preparation EGIS GYOGYSZERGYAR (HU) 1991-05-02 EP claimed
EP-0425283-A2 Novel triazolyl hydrazide derivatives and process for their preparation EGIS GYOGYSZERGYAR (HU) 1991-05-02 EP claimed
EP-4626419-A1 EIF4A1 INHIBITORS WITH ANTITUMOR ACTIVITY The United States Government as represented by the Department of Veterans Affairs (US) 2025-10-08 EP disclosed
CN-115490644-B 1,2, 3-Triazole-4-hydrazide Schiff base fluorescent probe and preparation method and application thereof 海南师范大学 2024-09-24 CN disclosed
CN-115490644-B 1,2, 3-Triazole-4-hydrazide Schiff base fluorescent probe and preparation method and application thereof 海南师范大学 2024-09-24 CN disclosed
WO-2024118667-A1 EIF4A1 INHIBITORS WITH ANTITUMOR ACTIVITY THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2024-06-06 WO disclosed
EP-0425282-A2 Triazolo derivatives and process for their preparation EGIS GYOGYSZERGYAR (HU) 1991-05-02 EP disclosed
EP-0425283-A2 Novel triazolyl hydrazide derivatives and process for their preparation EGIS GYOGYSZERGYAR (HU) 1991-05-02 EP disclosed
EP-0425283-A2 Novel triazolyl hydrazide derivatives and process for their preparation EGIS GYOGYSZERGYAR (HU) 1991-05-02 EP disclosed
EP-0425283-A2 Novel triazolyl hydrazide derivatives and process for their preparation EGIS GYOGYSZERGYAR (HU) 1991-05-02 EP disclosed