Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 11/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463681 | 0.78 | MAPT (0.50) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL30335572 | 0.78 | MAPT (0.50) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL87693 | 0.78 | MAPT (0.50) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL8085425 | 0.77 | ADRA2A (0.47) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL28520045 | 0.77 | ADRA2A (0.52) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL30716827 | 0.75 | MAPT (0.48) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL31330119 | 0.74 | ADRA2A (0.49) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL180196 | 0.74 | ADRA2A (0.53) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL22026140 | 0.74 | ADRA2A (0.41) | ADRA2AADRA2CADRA2BADRA1DADRA1A | |
| SCHEMBL22977483 | 0.74 | ADRA2A (0.49) | ADRA2AADRA2CADRA2BADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212147-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Hongyun Biotech Co., Ltd. (CN) | 2023-07-06 | — | — | US | disclosed |
| WO-2022221071-A1 | ALPHA2 ADRENERGIC AGONIST CODRUGS CONJUGATED WITH MUSCARINIC AGONIST DRUGS | ADS THERAPEUTICS LLC (US) | 2022-10-20 | — | — | WO | disclosed |
| US-9434701-B2 | Aminoquinoxaline derivatives for treatment of neurodegenerative diseases | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212147-A1 | ALKENYL PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | WEE1, EGFR, WEE2 | ADRA2A 4681/4885ADRA2C 4280/4885ADRA2B 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.