Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pradigastat SCHEMBL1289309 | 0.89 | DGAT1 (1.00) | DGAT1SOAT1 | |
| Pradigastat SCHEMBL16104874 | 0.89 | DGAT1 (1.00) | DGAT1SOAT1 | |
| Pradigastat SCHEMBL29358725 | 0.89 | DGAT1 (1.00) | DGAT1SOAT1 | |
| Pradigastat SCHEMBL180536 | 0.89 | DGAT1 (1.00) | DGAT1SOAT1 | |
| SCHEMBL181168 | 0.85 | DGAT1 (0.81) | DGAT1SOAT1 | |
| SCHEMBL181129 | 0.85 | DGAT1 (0.75) | DGAT1SOAT1 | |
| SCHEMBL31326545 | 0.84 | DGAT1 (0.82) | DGAT1SOAT1 | |
| SCHEMBL15445225 | 0.84 | DGAT1 (0.82) | DGAT1SOAT1 | |
| SCHEMBL180809 | 0.84 | DGAT1 (0.82) | DGAT1SOAT1 | |
| SCHEMBL13664086 | 0.84 | DGAT1 (0.82) | DGAT1SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402319-A1 | DGAT Inhibitors | Novartis AG (CH) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402318-A1 | DGAT inhibitors | Novartis AG (CH) | 2012-01-04 | — | — | EP | disclosed |