SCHEMBL18083593

SCHEMBL18083593

CCCc1ccc(-c2cc(F)c(-c3cc(F)c(F)c(F)c3)c(I)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.38
RARA P10276 1/20 0.38
RARG P13631 1/20 0.38
MCL1 Q07820 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
TP53 P04637 1/20 0.35
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ANPEP P15144 5/20 0.34
MAOB P27338 1/20 0.33
MAPT P10636 1/20 0.33
GFER P55789 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CNR2 P34972 1/20 0.32
CYP17A1 P05093 1/20 0.32
CYP21A2 P08686 1/20 0.32
CYP11B1 P15538 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15965523 0.89 RARB (0.42) RARBRARARARGMCL1NPC1
SCHEMBL16488492 0.89 RARB (0.42) RARBRARARARGMCL1NPC1
SCHEMBL14525745 0.86 RARB (0.46) RARBRARARARGMCL1NPC1
SCHEMBL16258127 0.86 RARB (0.46) RARBRARARARGMCL1NPC1
SCHEMBL9764255 0.86 RARB (0.46) RARBRARARARGMCL1NPC1
SCHEMBL17108404 0.81 RARB (0.40) RARBRARARARGMCL1NPC1
SCHEMBL16488494 0.80 RARB (0.50) RARBRARARARGNPC1RAB9A
SCHEMBL16104422 0.80 RARB (0.50) RARBRARARARGNPC1RAB9A
SCHEMBL16257979 0.79 RARB (0.41) RARBRARARARGMCL1NPC1
SCHEMBL21626078 0.79 RARB (0.38) RARBRARARARGMCL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2703473-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DAINIPPON INK & CHEMICALS (JP) 2016-09-21 EP disclosed