Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559509 | 0.89 | LPL (0.43) | NPC1RAB9ATP53PKMSMN1; SMN2 | |
| SCHEMBL16488492 | 0.88 | RARB (0.42) | RARBNPC1RAB9ARARARARG | |
| SCHEMBL15965523 | 0.88 | RARB (0.42) | RARBNPC1RAB9ARARARARG | |
| SCHEMBL9764255 | 0.87 | RARB (0.46) | RARBNPC1RAB9ARARARARG | |
| SCHEMBL14525745 | 0.87 | RARB (0.46) | RARBNPC1RAB9ARARARARG | |
| SCHEMBL16258127 | 0.87 | RARB (0.46) | RARBNPC1RAB9ARARARARG | |
| SCHEMBL16257979 | 0.81 | RARB (0.41) | RARBNPC1RAB9ARARARARG | |
| SCHEMBL18083593 | 0.81 | RARB (0.38) | RARBNPC1RAB9ARARARARG | |
| SCHEMBL17356571 | 0.79 | GCGR (0.32) | — | |
| SCHEMBL12566384 | 0.79 | RARB (0.45) | RARBNPC1RAB9ARARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906662-B1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |
| US-20150303397-A1 | INORGANIC BARRIER LAYERS | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150303397-A1 | INORGANIC BARRIER LAYERS | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150270489-A1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150270489-A1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |