Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27636608 | 1.00 | TSHR (0.52) | TSHRTRPA1DPP4F2ALDH1A1 | |
| SCHEMBL27813346 | 0.97 | TSHR (0.50) | TSHRTRPA1DPP4F2ALDH1A1 | |
| SCHEMBL9670939 | 0.80 | TSHR (0.36) | TSHRTRPA1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1967467 | 0.77 | ALDH1A1 (0.32) | TSHRTRPA1ALDH1A1 | |
| SCHEMBL10905926 | 0.77 | PTGS1 (0.49) | TSHRTRPA1ALDH1A1HTTLMNA | |
| SCHEMBL8010946 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HTTLMNASMN1; SMN2NPC1 | |
| SCHEMBL11019339 | 0.75 | TSHR (0.48) | TSHRTRPA1DPP4F2ALDH1A1 | |
| SCHEMBL27810840 | 0.75 | TSHR (0.48) | TSHRTRPA1DPP4F2ALDH1A1 | |
| SCHEMBL28303220 | 0.75 | CYP2A6 (0.38) | TRPA1ALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL3061003 | 0.75 | GAA (0.42) | TSHRALDH1A1HTTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118258909-A | Method for measuring content of p-cyanobenzyl chloride and isomers thereof in letrozole | 河北以岭医药研究院有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-116143701-A | Method for recycling waste residues generated in production of cyanobenzyl chloride | 吴桥县六合德利化工有限责任公司 | 2023-05-23 | — | — | CN | claimed |
| CN-216778821-U | Reation kettle is used in production of o cyano chlorobenzyl convenient to maintenance and clearance | 山东嘉瑞化工有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-112794827-A | High-weather-resistance and aging-resistance grafted dibenzoxazole stilbene type fluorescent whitening agent and preparation method thereof | 杭州劲瑞新材料有限公司 | 2021-05-14 | — | — | CN | claimed |
| CN-112645869-A | Preparation method of chlorpheniramine maleate intermediate | 北京悦康科创医药科技股份有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-108709944-B | Method for simultaneously detecting 6 chlorobenzene acetonitrile serving as nitrogenous aromatic disinfection by-product in drinking water | 同济大学 | 2021-02-12 | — | — | CN | claimed |
| CN-110526836-A | A kind of synthetic method of pair of cyano benzyl chloride | WUXUE YANGTAI CHEMICAL CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-110526829-A | The synthetic method of one inter-species cyano benzyl chloride | WUXUE YANGTAI CHEMICAL CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-208250198-U | A kind of device being continuously synthesizing to for imatinib mesylate | 江苏八巨药业有限公司 | 2018-12-18 | — | — | CN | claimed |
| CN-106831814-B | A kind of thieno [3,2-d] miazines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2018-11-23 | — | — | CN | claimed |
| CN-106117242-B | Tetrahydric thiapyran miazines derivative and the preparation method and application thereof | 山东大学 | 2018-08-03 | — | — | CN | claimed |
| CN-106087389-B | Preparation method of flame-retardant polyurethane synthetic leather | 嘉善沣德家具有限公司 | 2018-07-17 | — | — | CN | claimed |
| CN-108218896-A | A kind of Thiazolopyrimidine HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2018-06-29 | — | — | CN | claimed |
| CN-108218890-A | A kind of five yuan of non-aromatic ring miazines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2018-06-29 | — | — | CN | claimed |
| US-5648540-A | Amine preparation | NPS PHARMACEUTICALS, INC. (US) | 1997-07-15 | — | — | US | claimed |
| US-5565602-A | REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-15 | — | — | US | claimed |
| US-5504253-A | Amine preparation | NPS PHARMACEUTICALS, INC. (US) | 1996-04-02 | — | — | US | claimed |
| WO-1996002492-A1 | METHOD OF MAKING A BENZYLPROPANAMINE | NSP PHARMACEUTICALS, INC. (US) | 1996-02-01 | — | — | WO | claimed |
| EP-0045088-B1 | PROCESS FOR PREPARING SUBSTITUTED P-CHLOROPHENYL ALIPHATIC NITRILES | STAUFFER CHEMICAL COMPANY (US) | 1984-06-20 | — | — | EP | claimed |
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | claimed |