Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10182559 | 0.92 | TOP1 (0.62) | TOP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10149074 | 0.89 | TOP1 (0.59) | TOP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3860585 | 0.89 | NQO2 (0.60) | TOP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16681524 | 0.85 | TOP1 (0.66) | TOP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18085802 | 0.81 | MAPT (0.55) | TOP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17570205 | 0.80 | KMT2A (0.70) | TOP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10149369 | 0.79 | TOP1 (0.59) | TOP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL18085804 | 0.79 | LMNA (0.57) | TOP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16681364 | 0.79 | LMNA (0.77) | TOP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL16677946 | 0.79 | LMNA (0.72) | TOP1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077089-B1 | METHOD OF FORMING A COMPOSITE POLYAMIDE MEMBRANE TREATED WITH DIHYROXYARYL COMPOUNDS AND NITROUS ACID | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-02-28 | — | — | EP | disclosed |
| US-9452391-B1 | Composite polyamide membrane treated with dihyroxyaryl compounds and nitrous acid | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-09-27 | — | — | US | disclosed |
| US-9452391-B1 | Composite polyamide membrane treated with dihyroxyaryl compounds and nitrous acid | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-09-27 | — | — | US | disclosed |
| US-20160271569-A1 | COMPOSITE POLYAMIDE MEMBRANE TREATED WITH DIHYROXYARYL COMPOUNDS AND NITROUS ACID | THE DOW CHEMICAL COMPANY | 2016-09-22 | — | — | US | disclosed |
| US-20160271569-A1 | COMPOSITE POLYAMIDE MEMBRANE TREATED WITH DIHYROXYARYL COMPOUNDS AND NITROUS ACID | THE DOW CHEMICAL COMPANY | 2016-09-22 | — | — | US | disclosed |