Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353879 | 0.91 | HPGD (0.51) | PKMKMT2AMEN1SMN1; SMN2TAS2R14 | |
| SCHEMBL1811639 | 0.83 | PTGDR2 (0.48) | PKMKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL3904637 | 0.81 | BRD4 (0.50) | PKMKMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL1843321 | 0.81 | FFAR4 (0.43) | PKMSMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL1819937 | 0.78 | BRD4 (0.52) | MAPTALDH1A1 | |
| SCHEMBL3913785 | 0.77 | PTGDR2 (0.48) | PKMKMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL3909056 | 0.77 | BRD4 (0.40) | PKMSMN1; SMN2TSHRTP53ALDH1A1 | |
| SCHEMBL3904603 | 0.77 | MAPT (0.46) | PKMKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL3915102 | 0.76 | PTGDR2 (0.48) | PKMKMT2AMEN1TSHRMAPT | |
| SCHEMBL3910618 | 0.76 | SGK1 (0.41) | PKMSMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4682207-B2 | — | — | 2011-05-11 | — | — | JP | claimed |
| EP-1797042-B1 | INDOZOLONE DERIVATIVES AS 11B-HSD1 INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-01-07 | — | — | EP | claimed |