SCHEMBL1808752

SCHEMBL1808752

CC(C)OC(=O)c1cc(N)c(Cl)c(N)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.56
CA1 P00915 6/20 0.56
CA2 P00918 6/20 0.56
CA7 P43166 6/20 0.56
CA9 Q16790 6/20 0.56
CA14 Q9ULX7 6/20 0.56
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
PTPN11 Q06124 2/20 0.40
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPT P10636 1/20 0.40
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064984 0.83 CA12 (0.63) CA12CA1CA2CA7CA9
SCHEMBL5924235 0.83 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL27880035 0.82 CA12 (0.37) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL9064994 0.81 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL9328779 0.81 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL5374614 0.81 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL5924284 0.80 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL16606258 0.80 CA12 (0.75) CA12CA1CA2CA7CA9
SCHEMBL11651683 0.79 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL5219803 0.79 KDM4E (0.56) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0579989-B1 Polyurethaneurea elastomer IHARA CHEMICAL IND CO (JP) 1997-09-03 EP claimed
US-5410009-A Impact resilience; flexural properties IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-04-25 US claimed
EP-0579989-A1 Polyurethaneurea elastomer IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1994-01-26 EP claimed
US-11912813-B2 Urethane resin using polyrotaxane, and pad for polishing TOKUYAMA CORPORATION (JP) 2024-02-27 US disclosed
CN-111954691-B Urethane resin using polyrotaxane and polishing pad 株式会社德山 2022-04-22 CN disclosed
US-20210155736-A1 URETHANE RESIN USING POLYROTAXANE, AND PAD FOR POLISHING TOKUYAMA CORPORATION (JP) 2021-05-27 US disclosed
EP-3778688-A1 URETHANE RESIN USING POLYROTAXANE, AND PAD FOR POLISHING Tokuyama Corporation (JP) 2021-02-17 EP disclosed
CN-111954691-A Urethane resin using polyrotaxane and polishing pad 株式会社德山 2020-11-17 CN disclosed
EP-1715980-B1 BASE PAD POLISHING PAD AND MULTI-LAYER PAD COMPRISING THE SAME SKC CO LTD (KR) 2011-05-18 EP disclosed
CN-100475447-C Base pad of polishing pad and multi-layer pad comprising the same SKC CO LTD (KR) 2009-04-08 CN disclosed
US-7381121-B2 Base pad polishing pad and multi-layer pad comprising the same SKC CO., LTD. (KR) 2008-06-03 US disclosed
EP-1715980-A1 BASE PAD POLISHING PAD AND MULTI-LAYER PAD COMPRISING THE SAME SKC Co., Ltd. (KR) 2006-11-02 EP disclosed
WO-2005077602-A1 BASE PAD POLISHING PAD AND MULTI-LAYER PAD COMPRISING THE SAME SKC CO., LTD. (KR) 2005-08-25 WO disclosed
EP-0579989-B1 Polyurethaneurea elastomer IHARA CHEMICAL IND CO (JP) 1997-09-03 EP disclosed
EP-0538850-B1 New polyurea resins and their preparation and use IHARA CHEMICAL IND CO (JP) 1997-01-22 EP disclosed
US-5410009-A Impact resilience; flexural properties IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-04-25 US disclosed
US-5319058-A Improved heat resistance when polyisocyanate component is a combination of an aliphatic diisocyanate and a cyclic trimer of an aliphatic polyisocyanate IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1994-06-07 US disclosed
EP-0579989-A1 Polyurethaneurea elastomer IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1994-01-26 EP disclosed
EP-0538850-A2 New polyurea resins and their preparation and use IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 1993-04-28 EP disclosed
US-4520186-A IMPROVING MECHANICAL PROPERTIES OF ELASTOMERS BAYER AKTIENGESELLSCHAFT (DE) 1985-05-28 US disclosed