Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10410179 | 0.98 | KDM4E (0.55) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL22081924 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL31161652 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL28665944 | 0.89 | KDM4E (0.59) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL31161931 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL15407272 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL31325054 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL1457740 | 0.87 | GAA (0.53) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL11543864 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL1634319 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1MAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220229391-A1 | ELASTIC BODY FOR BLADES AND CLEANING BLADE USING THIS ELASTIC BODY | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2022-07-21 | — | — | US | disclosed |
| CN-113892063-A | Elastic body for blade and cleaning blade using the same | 阪东化学株式会社 | 2022-01-04 | — | — | CN | disclosed |
| US-7253198-B2 | Hydroxyethylamine derivatives for the treatment of Alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2007-08-07 | — | — | US | disclosed |
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |
| CN-1735592-A | Hydroxyethylamine derivatives for the treatment of alzheimer's disease | GLAXO GROUP LTD (GB) | 2006-02-15 | — | — | CN | disclosed |
| US-20060025459-A1 | Hydroxyethylamine derivatives for the treatment of alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2006-02-02 | — | — | US | disclosed |
| EP-1567488-A1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LIMITED (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050619-A1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LIMITED (GB) | 2004-06-17 | — | — | WO | disclosed |
| EP-0315112-B1 | NOVEL AMIDE COMPOUNDS | Toyo Boseki Kabushiki Kaisha (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-5106943-A | Molding materials; blend of trimer of polyisocyanate, epoxy compounds, and aromatic polyamine | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| US-4281151-A | ANTIALLERGENS, ANTIANAPHYLACTIC AGENTS | THE UPJOHN COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4251454-A | MADE FROM ANILINOMETHYLENE CHLORO-AMINO-HYDROCINNAMONITRILE | HOFFMANN-LA ROCHE INC. (US) | 1981-02-17 | — | — | US | disclosed |
| US-4186127-A | ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1980-01-29 | — | — | US | disclosed |
| US-4159278-A | PROPHYAXIS, ANTIALLERGENS, SENSITIZATION | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4107151-A | FROM POLYISOCYANATE, CHAIN POLYOL, AROMATIC DIAMINE, POLYOL OR AMINO ALCOHOL WITH URETHANE BOND | IHARA CHEMICAL COMPANY CO., LTD. (JP) | 1978-08-15 | — | — | US | disclosed |
| US-4095028-A | PROPHYLAXIS, ALLERGIES | THE UPJOHN COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4089973-A | Cyano phenylene dioxamic acid compounds used in the treatment of allergy | THE UPJOHN COMPANY (US) | 1978-05-16 | — | — | US | disclosed |
| US-4039543-A | SUBSTITUTED BY AMINE, N-RING, AMIDE, CARBAMATE, UREA | HOFFMANN-LA ROCHE INC. (US) | 1977-08-02 | — | — | US | disclosed |
| US-3993679-A | ANTIALLERGY | THE UPJOHN COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
| US-3988268-A | Polyurethane foam plastics which contain ionic groups | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025459-A1 | Hydroxyethylamine derivatives for the treatment of alzheimer's disease | BACE2, PSEN2, BACE1 | KDM4E 1129/4885ALDH1A1 3102/4885MAPT 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.