SCHEMBL1808757

SCHEMBL1808757

[CH2]c1c(C)c(F)c(F)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL117384 0.83
SCHEMBL7926204 0.73 GRIN2D (0.32)
SCHEMBL43508 0.73 GRIN2D (0.32)
SCHEMBL3043216 0.73
SCHEMBL107094 0.73 TAS1R3 (0.33)
SCHEMBL12787322 0.70
SCHEMBL12256409 0.70 TAS1R3 (0.32)
SCHEMBL926802 0.69 TAS1R3 (0.35)
SCHEMBL456535 0.69
SCHEMBL9766097 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0295839-A2 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-21 EP claimed
EP-0221635-A1 Fluoro alcohols and insecticidal esters thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-05-13 EP claimed
EP-1915331-B1 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL SHOWA DENKO KK (JP) 2013-07-10 EP disclosed
US-7939695-B2 Production process of nucleus-halogenated methylbenzyl alcohol SHOWA DENKO K.K. (JP) 2011-05-10 US disclosed
CN-101193843-B Production process of nucleus-halogenated methylbenzyl alcohol SHOWA DENKO KK 2011-05-04 CN disclosed
US-20100145106-A1 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2010-06-10 US disclosed
CN-101193843-A Production process of nucleus-halogenated methylbenzyl alcohol SHOWA DENKO KK (JP) 2008-06-04 CN disclosed
EP-1915331-A2 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL Showa Denko K.K. (JP) 2008-04-30 EP disclosed
WO-2006137348-A2 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2006-12-28 WO disclosed
US-6828467-B2 Industrial process of the hydrogenolysis of one hydroxyl or methanol group of a fluorinated benzenedimethanol carried out in a solvent in the presence of a catalyst; 2,3,5,6-tetra-fluorobenzyl alcohol from the 4-methyl derivative SHOWA DENKO K.K. (JP) 2004-12-07 US disclosed
EP-1322584-B1 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO KK (JP) 2004-11-24 EP disclosed
US-20040010167-A1 Process for producing fluorinated methyl-benzyl alcohol SHOWA DENKO K.K. (JP) 2004-01-15 US disclosed
EP-1322584-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL Showa Denko K.K. (JP) 2003-07-02 EP disclosed
WO-2002026678-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2002-04-04 WO disclosed
US-5010200-A Insecticide intermediates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-04-23 US disclosed
US-4962109-A MITICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-09 US disclosed
EP-0221635-B1 FLUORO ALCOHOLS AND INSECTICIDAL ESTERS THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-03-14 EP disclosed
EP-0295839-A2 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-12-21 EP disclosed
US-4714790-A Fluoro alcohols and insecticidal esters thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-12-22 US disclosed
EP-0221635-A1 Fluoro alcohols and insecticidal esters thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-05-13 EP disclosed