Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15368094 | 0.95 | MAPT (0.49) | MAPTCYP1A2 | |
| SCHEMBL19380046 | 0.85 | MAPT (0.53) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL15457901 | 0.83 | MAPT (0.54) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL11369105 | 0.82 | MAPT (0.50) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL15368083 | 0.81 | MAPT (0.57) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL15727951 | 0.81 | MAPT (0.57) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL8455180 | 0.81 | CYP1A2 (0.59) | MAPTCYP1A2 | |
| SCHEMBL18360766 | 0.80 | MAPT (0.55) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL19262493 | 0.80 | MAPT (0.48) | MAPTCYP1A2 | |
| SCHEMBL15934421 | 0.79 | MAPT (0.44) | MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160272346-A1 | FILLING DEVICE AND USE THEREOF FOR DISPENSING A FLUID | MERCK PATENT GMBH (DE) | 2016-09-22 | — | — | US | disclosed |