Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18360766 | 0.84 | MAPT (0.55) | MAPTTSHRCYP1A2LMNAMAPK1 | |
| SCHEMBL15457901 | 0.83 | MAPT (0.54) | MAPTTSHRCYP1A2LMNAMAPK1 | |
| SCHEMBL15368083 | 0.81 | MAPT (0.57) | MAPTTSHRCYP1A2LMNAMAPK1 | |
| SCHEMBL19380046 | 0.81 | MAPT (0.53) | MAPTTSHRCYP1A2LMNAMAPK1 | |
| SCHEMBL18088053 | 0.81 | MAPT (0.53) | MAPTTSHRCYP1A2LMNAMAPK1 | |
| SCHEMBL8455180 | 0.81 | CYP1A2 (0.59) | MAPTCYP1A2 | |
| SCHEMBL22127323 | 0.80 | MAPT (0.41) | MAPTESR2BRD4 | |
| SCHEMBL11369105 | 0.79 | MAPT (0.50) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL13464005 | 0.79 | MAPT (0.50) | MAPTCYP1A2LMNAMAPK1HTT | |
| SCHEMBL9407037 | 0.78 | CYP1A2 (0.58) | MAPTTSHRCYP1A2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9234136-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-01-12 | — | — | US | disclosed |
| US-20140138581-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-05-22 | — | — | US | disclosed |