SCHEMBL18088441

SCHEMBL18088441

O=C(O)CCCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCO)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.65
▸ NOD1 Q9Y239 3/20 0.44
▸ FOLH1 Q04609 3/20 0.42
▸ CCKAR P32238 3/20 0.42
▸ CCKBR P32239 3/20 0.42
▸ GLO1 Q04760 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13908024 1.00 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL16153068 1.00 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL16182607 1.00 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL16182606 1.00 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL13184651 1.00 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL22402567 1.00 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL16426625 1.00 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL12686659 1.00 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL12686635 1.00 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR
SCHEMBL15358601 0.96 GLP1R (0.65) GLP1RNOD1FOLH1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200407409-A1 EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS CHEN JIANHE (CN) 2020-12-31 — — US disclosed
US-20160271263-A1 Acylated Glucagon Analogues NOVO NORDISK AS (DK) 2016-09-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160271263-A1 Acylated Glucagon Analogues GLP1R, GCG, IAPP GLP1R 1/4885NOD1 2294/4885FOLH1 352/4885
US-20200407409-A1 EGF(A) ANALOGUES WITH FATTY ACID SUBSTITUENTS EGFR, LDLR, FFAR2 GLP1R 39/4885NOD1 4794/4885FOLH1 1459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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