Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14607759 | 0.84 | ATM (0.44) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL508551 | 0.82 | ATM (0.45) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL13116784 | 0.80 | CA1 (0.45) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL21452685 | 0.80 | ATM (0.44) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL9893075 | 0.80 | EPHX2 (0.67) | EPHX2EPHX1 | |
| SCHEMBL508550 | 0.80 | ATM (0.44) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL14025208 | 0.80 | ATM (0.44) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL14252483 | 0.80 | ATM (0.44) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL13654292 | 0.80 | ATM (0.44) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL50350 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070085-A1 | FLAP MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2016-09-21 | — | — | EP | disclosed |