Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13654467 | 0.88 | CA1 (0.46) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL13382861 | 0.88 | CA1 (0.46) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL18091012 | 0.80 | ATM (0.45) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL508551 | 0.80 | ATM (0.45) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL13654294 | 0.80 | LTA4H (0.38) | EPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL12425051 | 0.80 | EPHX1 (0.37) | EPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL7895774 | 0.79 | EPHX2 (0.49) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL21882071 | 0.78 | HTT (0.35) | EPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL508550 | 0.78 | ATM (0.44) | ATMEPHX2EPHX1ALDH1A1KDM4E | |
| SCHEMBL21452685 | 0.78 | ATM (0.44) | ATMEPHX2EPHX1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021074227-A1 | 2-METHYL-AZA-QUINAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-22 | — | — | WO | disclosed |
| EP-2882733-B1 | SUBSTITUTED AZINES AS PESTICIDES | NOVARTIS TIERGESUNDHEIT AG (CH) | 2017-04-26 | — | — | EP | disclosed |
| WO-2009123986-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-08 | — | — | WO | disclosed |