Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18092022 | 0.91 | GABRA5 (0.47) | GABRA5GABRA1 | |
| SCHEMBL18092030 | 0.89 | GABRA5 (0.52) | GABRA5 | |
| SCHEMBL18092009 | 0.87 | GABRA5 (0.53) | GABRA5GABRA1 | |
| SCHEMBL18091985 | 0.87 | GABRA5 (0.48) | GABRA5 | |
| SCHEMBL285762 | 0.87 | GABRA5 (0.50) | GABRA5GABRA1 | |
| SCHEMBL18092056 | 0.87 | GABRA5 (0.55) | GABRA5GABRA1 | |
| SCHEMBL18091973 | 0.87 | GABRA5 (0.44) | GABRA5 | |
| SCHEMBL18091969 | 0.86 | GABRA5 (0.51) | GABRA5 | |
| SCHEMBL18092027 | 0.85 | GABRA5 (0.44) | GABRA5GABRA1 | |
| SCHEMBL18092049 | 0.84 | GABRA5 (0.47) | GABRA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427459-B1 | ISOXAZOLE-THIAZOLE DERIVATIVES AS GABA A RECEPTOR INVERSE AGONISTS FOR USE IN THE TREATMENT OF COGNITIVE DISORDERS | HOFFMANN LA ROCHE (CH) | 2016-09-28 | — | — | EP | claimed |