Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31688134 | 0.71 | NPC1 (0.38) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL5552840 | 0.69 | NPC1 (0.52) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL3292125 | 0.69 | NPC1 (0.52) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL779443 | 0.66 | NPC1 (0.58) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL29852852 | 0.66 | PTPN1 (0.33) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL561906 | 0.66 | PTPN1 (0.33) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL9345937 | 0.66 | KIF11 (0.33) | MAPTSMN1; SMN2 | |
| SCHEMBL19480532 | 0.64 | KIF11 (0.52) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL19389701 | 0.62 | TSHR (0.48) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL700444 | 0.62 | KIF11 (0.48) | NPC1RAB9AMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491078-B1 | POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING | ADDIVANT SWITZERLAND GMBH (CH) | 2016-09-28 | — | — | EP | claimed |
| EP-2057222-B2 | COMPOSITION COMPRISING LIQUID PHOSPHITE BLENDS AS STABILIZERS | ADDIVANT SWITZERLAND GMBH (CH) | 2017-03-01 | — | — | EP | disclosed |