Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443965 | 0.82 | CA12 (0.32) | CA12CA1CA2CA9CYP1A2 | |
| SCHEMBL6616782 | 0.72 | CYP1A2 (0.30) | CYP1A2SMN1; SMN2 | |
| SCHEMBL7647670 | 0.72 | MAPT (0.39) | CA12CA1CA2CA9CYP1A2 | |
| Hydrochloric Acid SCHEMBL7096663 | 0.71 | — | — | |
| SCHEMBL30047108 | 0.71 | AXL (0.31) | CA12CA1CA2CA9 | |
| Quinoline SCHEMBL27947349 | 0.70 | ALDH1A1 (0.52) | CYP1A2SMN1; SMN2 | |
| SCHEMBL21319387 | 0.69 | CDC25B (0.41) | CA12CA1CA2CA9CYP1A2 | |
| SCHEMBL7056579 | 0.69 | CDC25B (0.41) | CA12CA1CA2CA9CYP1A2 | |
| SCHEMBL7056574 | 0.69 | CDC25B (0.41) | CA12CA1CA2CA9CYP1A2 | |
| SCHEMBL3293742 | 0.68 | MAPT (0.47) | CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113788825-B | Heteroaromatic compounds as VANIN inhibitors | 勃林格殷格翰国际有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-103857681-B | It is used as the new big ring of factor XI, plasma thromboplastin antecedent A inhibitor | 百时美施贵宝公司 | 2017-07-14 | — | — | CN | disclosed |
| US-20170158702-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KYRAS THERAPEUTICS, INC. | 2017-06-08 | — | — | US | disclosed |
| WO-2017043636-A1 | NOVEL BENZIMIDAZOLE COMPOUND AND PHARMACEUTICAL USE OF SAME | 大日本住友製薬株式会社 | 2017-03-16 | — | — | WO | disclosed |
| EP-2493888-A1 | BICYCLIC PYRIDINES AND ANALOGS AS SIRTUIN MODULATORS | Sirtris Pharmaceuticals, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011059839-A1 | BICYCLIC PYRIDINES AND ANALOGS AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| EP-0804440-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-11-05 | — | — | EP | disclosed |
| US-4029667-A | Certain 1-carbothioamides of 1,8-naphthyridines, pyrrolo(2,3-b)pyridines and pyrido(2,3-b)azepines | JOHN WYETH & BROTHER LIMITED (EN) | 1977-06-14 | — | — | US | disclosed |
| US-3960876-A | Certain 1-carbothioamides of 1,8-naphthyridines, pyrrolo(2,3-b)pyridines and pyrido(2,3-b)azepines | JOHN WYETH & BROTHER, LTD. (EN) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158702-A1 | MULTIVALENT RAS BINDING COMPOUNDS | KRAS, HRAS, NRAS | CA12 4020/4885CA1 4444/4885CA2 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.