Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20110460 | 0.92 | CYP3A4 (0.62) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 | |
| SCHEMBL18095579 | 0.91 | CYP3A4 (0.70) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 | |
| SCHEMBL18095577 | 0.88 | CYP3A4 (0.66) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 | |
| SCHEMBL2525660 | 0.88 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 | |
| SCHEMBL3755012 | 0.88 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 | |
| SCHEMBL15876419 | 0.88 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 | |
| SCHEMBL2525665 | 0.88 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 | |
| SCHEMBL15728982 | 0.88 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 | |
| SCHEMBL3755009 | 0.88 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 | |
| SCHEMBL2525662 | 0.88 | CYP3A4 (0.86) | CYP3A4CYP2C9P2RY2P2RY14P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407456-B2 | Nucleoside phosphoramidates useful for the treatment of viral infections and preparation thereof | QUIMICA SINTETICA, S.A. (ES) | 2019-09-10 | — | — | US | disclosed |
| US-20180118776-A1 | NUCLEOSIDE PHOSPHORAMIDATES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS AND PREPARATION THEREOF | QUIMICA SINTETICA S.A. (ES) | 2018-05-03 | — | — | US | disclosed |
| EP-3274356-A1 | NUCLEOSIDE PHOSPHORAMIDATES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS AND PREPARATION THEREOF | Química Sintética, S.A. (ES) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016151542-A1 | NUCLEOSIDE PHOSPHORAMIDATES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS AND PREPARATION THEREOF | QUIMICA SINTETICA, S.A. (ES) | 2016-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118776-A1 | NUCLEOSIDE PHOSPHORAMIDATES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS AND PREPARATION THEREOF | MTAP, PNP, UMPS | CYP3A4 347/4885CYP2C9 1702/4885P2RY2 936/4885 |
| US-10407456-B2 | Nucleoside phosphoramidates useful for the treatment of viral infections and preparation thereof | MTAP, PNP, UMPS | CYP3A4 347/4885CYP2C9 1702/4885P2RY2 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.