SCHEMBL18095877

SCHEMBL18095877

Cc1nc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2.OCc1nc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
VCP P55072 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15558834 0.96 VCP (0.73) VCP
SCHEMBL15549232 0.93 VCP (0.79) VCP
SCHEMBL18095897 0.88 VCP (0.85) VCP
SCHEMBL15421222 0.82 VCP (0.76) VCP
SCHEMBL15421210 0.82 VCP (1.00) VCP
SCHEMBL15438034 0.81 VCP (0.83) VCP
SCHEMBL17023306 0.80 VCP (0.71) VCP
SCHEMBL15421451 0.80 VCP (0.76) VCP
SCHEMBL15421347 0.80 VCP (0.77) VCP
SCHEMBL15421208 0.79 VCP (1.00) VCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016154110-A1 COMPANION DIAGNOSTIC FOR P97 INHIBITOR THERAPY AND METHODS OF USE THEREOF CLEAVE BIOSCIENCES, INC. (US) 2016-09-29 WO disclosed