SCHEMBL180960

SCHEMBL180960

c1ccc(CC2(Cc3ccccc3)COCCO2)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.39
MAOB P27338 7/20 0.39
HTR1A P08908 3/20 0.35
KDM1A O60341 4/20 0.33
ADRA1D P25100 1/20 0.33
SIGMAR1 Q99720 2/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1009707 0.98 MAOA (0.38) MAOAMAOBHTR1AKDM1AADRA1D
SCHEMBL1007966 0.98 MAOA (0.38) MAOAMAOBHTR1AKDM1AADRA1D
SCHEMBL1009359 0.98 MAOA (0.38) MAOAMAOBHTR1AKDM1AADRA1D
SCHEMBL706405 0.90 MAOA (0.35) MAOAMAOBHTR1AKDM1ASIGMAR1
SCHEMBL3886896 0.90 MAOA (0.39) MAOAMAOBHTR1AKDM1AADRA1D
SCHEMBL11267300 0.90 MAOA (0.35) MAOAMAOBHTR1AKDM1AADRA1D
SCHEMBL3885101 0.90 MAOA (0.35) MAOAMAOBHTR1APOLBNPSR1
SCHEMBL8019177 0.88 MAOA (0.34) MAOAMAOBSIGMAR1POLBNPSR1
SCHEMBL10974727 0.87 TDP1 (0.33) MAOAMAOBHTR1A
SCHEMBL8678876 0.85 MEN1 (0.36) MAOAMAOBSIGMAR1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118846246-A Medical polyimide catheter and preparation method and application thereof 宁波琳盛高分子材料有限公司 2024-10-29 CN claimed
CN-118852621-A Polyimide compound, medical polyimide catheter, and preparation methods and applications thereof 宁波琳盛高分子材料有限公司 2024-10-29 CN claimed
US-20240326017-A1 FIBER-ENCAPSULATED HYBRID MATERIALS FOR CAPTURE OF CARBON DIOXIDE UT BATTELLE LLC (US) 2024-10-03 US claimed
CN-112352331-A Formulations containing highly branched polymers, highly branched polymers and electro-optical devices containing such highly branched polymers 默克专利有限公司 2021-02-09 CN claimed
US-10267758-B2 Sensor element, method of making, and method of using the same 3M INNOVATIVE PROPERTIES, COMPANY (US) 2019-04-23 US claimed
EP-2880431-B1 PORTABLE ELECTRONIC DEVICE AND VAPOR SENSOR CARD 3M INNOVATIVE PROPERTIES CO (US) 2019-01-02 EP claimed
EP-1963852-B1 OPTOCHEMICAL SENSOR AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2018-09-19 EP claimed
EP-2864770-B1 SENSOR ELEMENT, METHOD OF MAKING, AND METHOD OF USING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2017-09-27 EP claimed
US-9702840-B2 Portable electronic device and vapor sensor card 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-07-11 US claimed
US-20150185175-A1 PORTABLE ELECTRONIC DEVICE AND VAPOR SENSOR CARD 3M INNOVATIVE PROPERTIES COMPANY 2015-07-02 US claimed
US-7691990-B2 Structure designed for adsorption of DNA intercalators CANON KABUSHIKI KAISHA (JP) 2010-04-06 US claimed
US-7556774-B2 Optochemical sensor and method of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-07-07 US claimed
EP-1963852-A1 OPTOCHEMICAL SENSOR AND METHOD OF MAKING THE SAME 3M Innovative Properties Company (US) 2008-09-03 EP claimed
WO-2007075273-A1 OPTOCHEMICAL SENSOR AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-07-05 WO claimed
US-20070140907-A1 OPTOCHEMICAL SENSOR AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2007-06-21 US claimed
US-6861527-B1 Nitration in a static micromixer MERCK PATENT GMBH (DE) 2005-03-01 US claimed
US-20030022335-A1 Novel polypeptides and methods for their use UNIVERSITY OF IOWA RESEARCH FOUNDATION 2003-01-30 US claimed
WO-2000037480-A1 NOVEL NAPHTHALENE DIOXYGENASE AND METHODS FOR THEIR USE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2000-06-29 WO claimed
EP-0193475-A1 Process for the acetoacetylation of aromatic compounds RHONE-POULENC CHIMIE (FR) 1986-09-03 EP claimed
US-4082807-A REACTING AN AROMATIC COMPOUND WITH AN ACETOACETYL FLUORIDE; HYDROGEN FLUORIDE HOECHST AKTIENGESELLSCHAFT (DT) 1978-04-04 US claimed