Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 5/20 | 1.00 |
| ▸ | CA2 | P00918 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18098767 | 0.91 | CA9 (0.83) | CA9CA2KDM4EMAPTGAA | |
| SCHEMBL3051727 | 0.88 | CA9 (0.82) | CA9CA2KDM4EMAPTGAA | |
| Hydrochloric Acid SCHEMBL10755161 | 0.87 | CA9 (0.81) | CA9CA2KDM4EMAPTGAA | |
| SCHEMBL3064371 | 0.86 | CA9 (0.76) | CA9CA2KDM4EMAPTGAA | |
| SCHEMBL3046704 | 0.85 | CA9 (0.74) | CA9CA2KDM4EMAPTGAA | |
| SCHEMBL3050097 | 0.82 | CA9 (1.00) | CA9CA2KDM4EMAPTGAA | |
| SCHEMBL3046074 | 0.80 | ABCB1 (0.67) | CA9CA2KDM4EMAPTGAA | |
| SCHEMBL3057030 | 0.79 | CA2 (0.66) | CA9CA2KMT2AMEN1CA7 | |
| SCHEMBL3051318 | 0.78 | CA9 (0.71) | CA9CA2KDM4EMAPTGAA | |
| SCHEMBL3051413 | 0.78 | CA2 (0.64) | CA9CA2KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155192-B1 | TETRAHYDROISOQUINOLINES AS TUMOUR GROWTH INHIBITORS | STERIX LTD (GB) | 2016-09-28 | — | — | EP | disclosed |