Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18098981 | 0.92 | NPC1 (0.32) | MAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL19244936 | 0.91 | MAP4K4 (0.32) | MAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL18099058 | 0.91 | NPC1 (0.31) | MAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL18098852 | 0.91 | ALDH1A1 (0.35) | MAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL18098976 | 0.91 | NPC1 (0.42) | MAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL18099012 | 0.91 | NPC1 (0.42) | MAP4K4NPC1RAB9ANLRP3 | |
| SCHEMBL18098949 | 0.89 | TLR2 (0.33) | — | |
| SCHEMBL18098966 | 0.89 | — | — | |
| SCHEMBL18098974 | 0.89 | TLR2 (0.33) | — | |
| SCHEMBL18098975 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |