SCHEMBL18100429

SCHEMBL18100429

Cl/C(=N\c1ccc(Cc2ccc(/N=C(\Cl)c3ccccc3)cc2)cc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 2/20 0.56
ADRA2A P08913 1/20 0.48
ADRA2B P18089 1/20 0.48
ADRA2C P18825 1/20 0.48
CYP2C9 P11712 1/20 0.43
CALM1 P0DP23 1/20 0.41
PLA2G10 O15496 1/20 0.40
PLA2G2A P14555 1/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
IDH1 O75874 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
SRD5A2 P31213 1/20 0.36
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
PLAU P00749 3/20 0.34
HTR3E A5X5Y0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18100425 0.88 MEN1 (0.48) SLC22A2LMNAMEN1KMT2APRSS1
SCHEMBL4624489 0.83 KMT2A (0.54) SLC22A2LMNAMEN1KMT2ATSHR
SCHEMBL4624494 0.83 KMT2A (0.54) SLC22A2LMNAMEN1KMT2ATSHR
SCHEMBL13585512 0.80 HTR3E (0.48) SLC22A2LMNAMEN1KMT2ATSHR
SCHEMBL13585511 0.80 HTR3E (0.48) SLC22A2LMNAMEN1KMT2ATSHR
SCHEMBL18100420 0.79 ESR1 (0.50) SLC22A2LMNAMEN1KMT2APLAU
SCHEMBL11385861 0.78 SLC22A2 (0.47) SLC22A2MEN1KMT2APLAUHTR3E
SCHEMBL11385863 0.78 SLC22A2 (0.47) SLC22A2MEN1KMT2APLAUHTR3E
SCHEMBL11582784 0.77 SLC22A2 (0.56) SLC22A2ADRA2AADRA2BADRA2CCYP2C9
SCHEMBL11582781 0.77 SLC22A2 (0.56) SLC22A2ADRA2AADRA2BADRA2CCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160280851-A1 IMINOETHER COMPOUND, POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCING CARBOXYLIC ACID ESTER, POLYESTER FILM, BACK SHEET FOR SOLAR CELL MODULE, AND SOLAR CELL MODULE FUJIFILM CORPORATION (JP) 2016-09-29 US disclosed
US-20160280851-A1 IMINOETHER COMPOUND, POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCING CARBOXYLIC ACID ESTER, POLYESTER FILM, BACK SHEET FOR SOLAR CELL MODULE, AND SOLAR CELL MODULE FUJIFILM CORPORATION (JP) 2016-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160280851-A1 IMINOETHER COMPOUND, POLYESTER RESIN COMPOSITION, METHOD FOR PRODUCING CARBOXYLIC ACID ESTER, POLYESTER FILM, BACK SHEET FOR SOLAR CELL MODULE, AND SOLAR CELL MODULE BRS3, RAD1, RAD51 SLC22A2 3162/4885ADRA2A 1925/4885ADRA2B 1349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.