Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25607195 | 0.98 | PRKDC (0.36) | PRKDCALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL9926880 | 0.97 | PRKDC (0.36) | PRKDCALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL25607198 | 0.97 | ALDH1A1 (0.35) | PRKDCALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL25844763 | 0.96 | ALDH1A1 (0.35) | PRKDCALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL18102227 | 0.96 | ALDH1A1 (0.35) | PRKDCALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL25607201 | 0.95 | AKT1 (0.36) | PRKDCALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL25607200 | 0.94 | PRKDC (0.35) | PRKDCALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL25607202 | 0.94 | AKT1 (0.36) | PRKDCALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL1186030 | 0.94 | PRKDC (0.36) | PRKDCALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL16705205 | 0.94 | AKT1 (0.35) | PRKDCALDH1A1KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071401-B1 | METHOD OF FORMING A PHOTOCHROMIC SEGMENTED MULTIFOCAL LENS | TRANSITIONS OPTICAL INC (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20160279886-A1 | METHOD OF FORMING A PHOTOCHROMIC SEGMENTED MULTIFOCAL LENS | TRANSITIONS OPTICAL, INC. | 2016-09-29 | — | — | US | disclosed |