Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | APP | P05067 | 4/20 | 0.61 |
| ▸ | INSR | P06213 | 3/20 | 0.47 |
| ▸ | VDR | P11473 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 4/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16997443 | 0.89 | MAPT (0.55) | MAPTAPPINSRVDRMEN1 | |
| SCHEMBL18102258 | 0.87 | APP (0.80) | MAPTAPPINSRMEN1LMNA | |
| SCHEMBL14562240 | 0.87 | APP (0.77) | MAPTAPPINSRMEN1LMNA | |
| SCHEMBL8995923 | 0.86 | MAPT (0.68) | MAPTAPPINSRVDRMEN1 | |
| SCHEMBL16253381 | 0.86 | MAPT (0.68) | MAPTAPPINSRVDRMEN1 | |
| SCHEMBL17320723 | 0.85 | MAPT (0.55) | MAPTAPPINSRVDRMEN1 | |
| SCHEMBL13235724 | 0.85 | MAPT (0.58) | MAPTAPPINSRVDRMEN1 | |
| Hydrochloric Acid SCHEMBL14675272 | 0.85 | MAPT (0.67) | MAPTAPPINSRVDRMEN1 | |
| Iodide SCHEMBL29249905 | 0.85 | MAPT (0.70) | MAPTAPPINSRVDRMEN1 | |
| Hydrochloric Acid SCHEMBL29429013 | 0.85 | MAPT (0.67) | MAPTAPPINSRVDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230341410-A1 | LUCIFERASE-BASED THERMAL SHIFT ASSAYS | PROMEGA CORPORATION | 2023-10-26 | — | — | US | disclosed |
| US-20160282360-A1 | LUCIFERASE-BASED THERMAL SHIFT ASSAYS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-09-29 | — | — | US | disclosed |