Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 6/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19999080 | 0.87 | PDE4B (0.72) | NAT1PDE4BPIM1MAOBCISD1 | |
| SCHEMBL18103030 | 0.83 | PDE4B (0.75) | NAT1PDE4BPIM1MAOBCISD1 | |
| Acetic Acid SCHEMBL5132123 | 0.77 | NAT1 (0.67) | NAT1PDE4BPIM1MAOBCISD1 | |
| SCHEMBL1449166 | 0.76 | NAT1 (0.74) | NAT1PDE4BPIM1MAOBCISD1 | |
| SCHEMBL18102942 | 0.76 | NAT1 (0.78) | NAT1PDE4BPIM1GSK3BPTP4A3 | |
| SCHEMBL3425968 | 0.76 | NAT1 (1.00) | NAT1PIM1GSK3BPTP4A3CA2 | |
| SCHEMBL3425971 | 0.76 | NAT1 (1.00) | NAT1PIM1GSK3BPTP4A3CA2 | |
| SCHEMBL15421702 | 0.76 | NAT1 (1.00) | NAT1PIM1GSK3BPTP4A3CA2 | |
| SCHEMBL18102921 | 0.75 | KMT2A (0.63) | NAT1PDE4BALDH1A1KMT2AGSK3B | |
| SCHEMBL18102951 | 0.74 | NAT1 (0.74) | NAT1PDE4BPIM1GSK3BPTP4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016154255-A1 | INHIBITORS OF THE NOTCH TRANSCRIPTIONAL ACTIVATION COMPLEX AND METHODS FOR USE OF THE SAME | UNIVERSITY OF MIAMI (US) | 2016-09-29 | — | — | WO | disclosed |