Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 14/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810374 | 1.00 | EGLN1 (0.43) | EGLN1BBOX1FTOKDM4CEGLN3 | |
| SCHEMBL1809460 | 0.88 | EGLN1 (0.43) | EGLN1BBOX1FTOKDM4CEGLN3 | |
| SCHEMBL1809456 | 0.88 | EGLN1 (0.43) | EGLN1BBOX1FTOKDM4CEGLN3 | |
| SCHEMBL1810099 | 0.84 | EGLN1 (0.51) | EGLN1BBOX1FTOKDM4CEGLN3 | |
| SCHEMBL1810108 | 0.84 | EGLN1 (0.51) | EGLN1BBOX1FTOKDM4CEGLN3 | |
| SCHEMBL1808840 | 0.83 | EGLN1 (0.45) | EGLN1BBOX1FTOKDM4CEGLN3 | |
| SCHEMBL1808766 | 0.83 | EGLN1 (0.45) | EGLN1BBOX1FTOKDM4CEGLN3 | |
| SCHEMBL1810533 | 0.80 | EGLN1 (0.67) | EGLN1BBOX1FTOEGLN3 | |
| SCHEMBL1810167 | 0.79 | EGLN1 (0.40) | EGLN1KDM4CKMT2A | |
| SCHEMBL1811027 | 0.75 | EGLN1 (0.50) | EGLN1BBOX1FTOKDM4CEGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | claimed |
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |