Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811763 | 0.82 | EGLN1 (0.43) | EGLN1COMTLCKCCNCCDK8 | |
| SCHEMBL1808323 | 0.81 | EGLN1 (0.42) | EGLN1COMTLCKCCNCCDK8 | |
| SCHEMBL1810374 | 0.79 | EGLN1 (0.43) | EGLN1KMT2AKDM4C | |
| SCHEMBL1810367 | 0.79 | EGLN1 (0.43) | EGLN1KMT2AKDM4C | |
| SCHEMBL1810533 | 0.79 | EGLN1 (0.67) | EGLN1 | |
| SCHEMBL1810341 | 0.75 | EGLN1 (0.40) | EGLN1COMTLCKKDM4ERCE1 | |
| SCHEMBL1811663 | 0.74 | EGLN1 (0.30) | EGLN1 | |
| SCHEMBL1809247 | 0.72 | KDM4E (0.47) | EGLN1LCKKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1808127 | 0.72 | HPGD (0.44) | CCNCCDK8KDM4ERCE1ALDH1A1 | |
| SCHEMBL1974306 | 0.72 | LCK (0.36) | EGLN1COMTLCKKDM4EGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056725-A1 | PYRIDINE DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2011-05-12 | — | — | WO | disclosed |