SCHEMBL18104403

SCHEMBL18104403

CCC(C)C(=O)Oc1ccc(/C=C/C(=O)OC)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.53
▸ KDM4E B2RXH2 2/20 0.53
▸ CA12 O43570 2/20 0.53
▸ CA1 P00915 2/20 0.53
▸ CA2 P00918 2/20 0.53
▸ CA7 P43166 2/20 0.53
▸ CA9 Q16790 2/20 0.53
▸ CA14 Q9ULX7 2/20 0.53
▸ TYR P14679 1/20 0.53
▸ TDP1 Q9NUW8 2/20 0.51
▸ LMNA P02545 1/20 0.51
▸ TAS1R3 Q7RTX0 3/20 0.49
▸ TAS1R1 Q7RTX1 3/20 0.49
▸ JAK2 O60674 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ HTT P42858 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ GSK3B P49841 1/20 0.48
▸ PTPN1 P18031 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14275401 0.86 KMT2A (0.59) MAPTTDP1LMNAALDH1A1SMN1; SMN2
SCHEMBL18104407 0.86 THRB (0.55) MAPTKDM4ECA12CA1CA2
SCHEMBL14275400 0.84 KMT2A (0.53) MAPTTDP1LMNAALDH1A1KMT2A
SCHEMBL17049386 0.84 KMT2A (0.44) MAPTKDM4ECA12CA1CA2
SCHEMBL14275402 0.81 CNR2 (0.47) MAPTPTPN1APPKMT2A
SCHEMBL8750848 0.81 MAPT (0.53) MAPTKDM4ECA12CA1CA2
SCHEMBL13750797 0.80 MAPT (0.64) MAPTLMNAALDH1A1KMT2AMEN1
SCHEMBL18104435 0.80 MAPT (0.64) MAPTLMNAALDH1A1KMT2AMEN1
SCHEMBL22268380 0.80 TTR (0.60) MAPTKDM4ELMNATAS1R3TAS1R1
SCHEMBL19244461 0.80 CA12 (0.55) MAPTKDM4ECA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160280999-A1 POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF FUJIFILM CORPORATION (JP) 2016-09-29 — — US disclosed
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