Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789961 | 0.85 | PTGS1 (0.39) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL2403909 | 0.85 | — | — | |
| SCHEMBL14414885 | 0.85 | PTGS1 (0.39) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL63679 | 0.85 | PTGS1 (0.39) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL25336178 | 0.83 | PTGS1 (0.38) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL9351921 | 0.83 | PTGS1 (0.38) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL11343102 | 0.83 | PTGS1 (0.38) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL9897194 | 0.83 | PTGS1 (0.38) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL8463674 | 0.83 | PTGS1 (0.38) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| Hydrazine SCHEMBL11671403 | 0.81 | LMNA (0.42) | PTGS1PDE4ALMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3075742-B1 | HIGH-SELECTIVITY CONTACT ACTIVATION INHIBITOR BASED ON INFESTIN-4 | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYU «GEMATOLOGICHESKAYA KORPORATSIYA» (RU) | 2019-04-17 | — | — | EP | disclosed |
| US-10006080-B2 | High-selectivity contact activation inhibitor based on infestin-4 | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYU “GEMATOLOGICHESKAYA KORPORATSIYA” (RU) | 2018-06-26 | — | — | US | disclosed |
| US-20160376634-A1 | HIGH-SELECTIVITY CONTACT ACTIVATION INHIBITOR BASED ON INFESTIN-4 | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYU <<GEMATOLOGICHESKAYA KORPORATSIYA (RU) | 2016-12-29 | — | — | US | disclosed |
| EP-3075742-A1 | HIGH-SELECTIVITY CONTACT ACTIVATION INHIBITOR BASED ON INFESTIN-4 | Obschestvo S Ogranichennoy Otvetstvennostyu «Gematologicheskaya Korporatsiya» (RU) | 2016-10-05 | — | — | EP | disclosed |