SCHEMBL18106934

SCHEMBL18106934

Cc1ccccc1OC(Cl)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 8/20 0.50
SLC6A4 P31645 7/20 0.50
SLC6A3 Q01959 7/20 0.50
CYP2D6 P10635 5/20 0.50
TSHR P16473 5/20 0.50
CYP3A4 P08684 4/20 0.50
CYP1A2 P05177 3/20 0.50
CHRM1 P11229 3/20 0.50
ADRA2B P18089 3/20 0.50
HTR2A P28223 3/20 0.50
HTR2C P28335 3/20 0.50
HRH1 P35367 3/20 0.50
OPRM1 P35372 3/20 0.50
DRD3 P35462 3/20 0.50
HTR2B P41595 3/20 0.50
KCNH2 Q12809 3/20 0.50
OPRK1 P41145 2/20 0.50
KLF10 Q13118 2/20 0.50
HRH3 Q9Y5N1 2/20 0.50
KMT2A Q03164 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4480102 0.79 SLC6A2 (0.53) SLC6A2SLC6A4SLC6A3CYP2D6TSHR
SCHEMBL31121337 0.79 TSHR (0.43) SLC6A2SLC6A4SLC6A3CYP2D6TSHR
SCHEMBL9707206 0.78 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3CYP2D6TSHR
SCHEMBL11233807 0.78 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3CYP2D6TSHR
SCHEMBL11020631 0.77 NISCH (0.45) SLC6A2SLC6A4SLC6A3CYP2D6TSHR
SCHEMBL11842410 0.77 SCN4A (0.39) SLC6A2SLC6A4SLC6A3CYP2D6TSHR
SCHEMBL8528086 0.76 SCN4A (0.51) SLC6A2SLC6A4SLC6A3CYP2D6TSHR
SCHEMBL3920124 0.76 TSHR (0.43) TSHRCYP3A4DRD3KMT2ALMNA
SCHEMBL28560112 0.74 SLC6A2 (0.56) SLC6A2SLC6A4SLC6A3CYP2D6TSHR
SCHEMBL28560113 0.74 SLC6A2 (0.56) SLC6A2SLC6A4SLC6A3CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2149545-B1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2016-10-05 EP disclosed