SCHEMBL4480102

SCHEMBL4480102

Cc1ccccc1OC(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 7/20 0.53
SLC6A4 P31645 6/20 0.53
SLC6A3 Q01959 6/20 0.53
CYP2D6 P10635 5/20 0.53
CYP3A4 P08684 4/20 0.53
TSHR P16473 4/20 0.53
CYP1A2 P05177 3/20 0.53
CHRM1 P11229 3/20 0.53
ADRA2B P18089 3/20 0.53
HTR2A P28223 3/20 0.53
HTR2C P28335 3/20 0.53
HRH1 P35367 3/20 0.53
OPRM1 P35372 3/20 0.53
DRD3 P35462 3/20 0.53
HTR2B P41595 3/20 0.53
KCNH2 Q12809 3/20 0.53
OPRK1 P41145 2/20 0.53
KLF10 Q13118 2/20 0.53
HRH3 Q9Y5N1 2/20 0.53
KMT2A Q03164 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9707206 0.81 SLC6A2 (0.51) SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4
SCHEMBL18106934 0.79 SLC6A2 (0.50) SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4
SCHEMBL8528086 0.79 SCN4A (0.51) SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4
SCHEMBL9853727 0.77 ESR2 (0.44) SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4
SCHEMBL9297488 0.77 ALDH1A1 (0.41) SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4
SCHEMBL9298647 0.77 IDO1 (0.44) SLC6A2SLC6A4SLC6A3CHRM1OPRM1
SCHEMBL28911420 0.77 TSHR (0.46) SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4
SCHEMBL3298569 0.76 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4
SCHEMBL13787614 0.76 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4
SCHEMBL28795114 0.75 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1498432-B1 PROCESS FOR PRODUCING HIGHLY FLOWABLE PROPYLENE POLYMER AND HIGHLY FLOWABLE PROPYLENE POLYMER IDEMITSU KOSAN CO (JP) 2009-09-02 EP disclosed
US-20050159566-A1 improved flexibility, and transparency, heat sealability and hot tackiness; good softness, a less stickiness, and an good compatibility with polyolefin resins; for sanitary materials, packing, bookbinding, fibers IDEMITSU KOSAN CO., LTD (JP) 2005-07-21 US disclosed
EP-1498432-A1 PROCESS FOR PRODUCING HIGHLY FLOWABLE PROPYLENE POLYMER AND HIGHLY FLOWABLE PROPYLENE POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 2005-01-19 EP disclosed
EP-0446720-A2 Novel brominated phenoxy compounds and processes for their preparation Bromine Compounds Ltd. (IL) 1991-09-18 EP disclosed
EP-0176366-B1 IMPREGNATED CAPACITOR NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-01-25 EP disclosed
US-4631632-A METALLIZED POLYPROPYLENE FILM IMPREGNATED WITH DIELECTRIC HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-12-23 US disclosed
EP-0176366-A2 Impregnated capacitor NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-04-02 EP disclosed