Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215071 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL8103993 | 0.88 | — | — | |
| SCHEMBL9210387 | 0.87 | KDM4E (0.64) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL9663829 | 0.87 | PTGS1 (0.75) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL9215059 | 0.87 | KDM4E (0.64) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL9370520 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL9217701 | 0.86 | ACAT1 (0.66) | KDM4E | |
| SCHEMBL8476295 | 0.86 | KDM4E (0.62) | KDM4EALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL9212895 | 0.86 | ACAT1 (0.66) | KDM4E | |
| SCHEMBL9213347 | 0.86 | ACAT1 (0.66) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493862-B1 | IMIDAZOLE DERIVATIVES AS IDO INHIBITORS | NEWLINK GENETICS CORP (US) | 2016-10-05 | — | — | EP | disclosed |