Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027548 | 0.92 | LTA4H (0.41) | LTA4HCA4TSHRMAPTCHRNB2 | |
| SCHEMBL5029761 | 0.92 | LTA4H (0.41) | LTA4HCA4TSHRMAPTCHRNB2 | |
| SCHEMBL5032246 | 0.86 | CA4 (0.46) | LTA4HCA4TSHRKCNA3KDM4E | |
| SCHEMBL5027493 | 0.86 | CA4 (0.46) | LTA4HCA4TSHRKCNA3KDM4E | |
| SCHEMBL5032266 | 0.80 | LTA4H (0.41) | LTA4HCA4TSHRMAPTCHRNB2 | |
| SCHEMBL18108458 | 0.78 | LTA4H (0.39) | LTA4HCA4TSHRMAPTCHRNB2 | |
| SCHEMBL29222960 | 0.78 | LTA4H (0.39) | LTA4HCA4TSHRMAPTCHRNB2 | |
| SCHEMBL5031033 | 0.77 | LTA4H (0.40) | LTA4HCA4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18108389 | 0.77 | LTA4H (0.38) | LTA4HCA4TSHRMAPTCHRNB2 | |
| SCHEMBL18108090 | 0.77 | LTA4H (0.38) | LTA4HCA4TSHRMAPTCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884928-B2 | Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group | BRIDGESTONE CORPORATION (JP) | 2018-02-06 | — | — | US | disclosed |
| US-20160289354-A1 | POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP | BRIDGESTONE CORPORATION (JP) | 2016-10-06 | — | — | US | disclosed |