Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 10/20 | 0.64 |
| ▸ | GLP1R | P43220 | 8/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31276572 | 0.87 | NOD1 (0.66) | NOD1GLP1REPHX2 | |
| SCHEMBL31276477 | 0.87 | NOD1 (0.66) | NOD1GLP1REPHX2 | |
| SCHEMBL5971031 | 0.87 | DPP4 (0.50) | NOD1 | |
| SCHEMBL5970256 | 0.87 | DPP4 (0.50) | NOD1 | |
| SCHEMBL24968497 | 0.87 | FOLH1 (0.55) | NOD1EPHX2 | |
| SCHEMBL31744954 | 0.87 | FOLH1 (0.55) | NOD1EPHX2 | |
| SCHEMBL5674457 | 0.87 | FOLH1 (0.55) | NOD1EPHX2 | |
| SCHEMBL20146969 | 0.85 | NOD1 (0.71) | NOD1GLP1R | |
| SCHEMBL20146947 | 0.85 | NOD1 (0.71) | NOD1GLP1R | |
| SCHEMBL16638268 | 0.85 | NOD1 (0.71) | NOD1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220054590-A1 | PROTOXIN-II VARIANTS AND METHODS OF USE THEREOF | JANSSEN BIOTECH, INC. | 2022-02-24 | — | — | US | disclosed |
| US-11083776-B2 | Protoxin-II variants and methods of use | JANSSEN BIOTECH, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| US-20200054712-A1 | PROTOXIN-II VARIANTS AND METHODS OF USE | JANSSEN BIOTECH, INC. | 2020-02-20 | — | — | US | disclosed |
| US-10463714-B2 | Protoxin-II variants and methods of use | JANSSEN BIOTECH, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| US-20160287666-A1 | PROTOXIN-II VARIANTS AND METHODS OF USE | JANSSEN BIOTECH, INC. | 2016-10-06 | — | — | US | disclosed |