SCHEMBL1811235

SCHEMBL1811235

NOC(=O)CCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.68
KEAP1 Q14145 1/20 0.59
ALDH1A1 P00352 3/20 0.55
FFAR1 O14842 2/20 0.55
HDAC2 Q92769 2/20 0.52
HDAC8 Q9BY41 2/20 0.52
HDAC6 Q9UBN7 2/20 0.52
KMT2A Q03164 2/20 0.51
L3MBTL1 Q9Y468 4/20 0.50
MAPT P10636 3/20 0.50
HDAC1 Q13547 2/20 0.50
HTT P42858 2/20 0.50
POLB P06746 1/20 0.50
HDAC3 O15379 1/20 0.50
MAPK1 P28482 1/20 0.50
ADRA1A P35348 1/20 0.50
HDAC4 P56524 1/20 0.50
SLC6A3 Q01959 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21546065 0.98 TDP1 (0.66) TDP1KEAP1ALDH1A1FFAR1HDAC2
Hydrochloric Acid SCHEMBL28018100 0.98 TDP1 (0.66) TDP1KEAP1ALDH1A1FFAR1HDAC2
SCHEMBL15976585 0.89 FFAR1 (0.65) TDP1FFAR1HDAC2HDAC1HTT
SCHEMBL20815410 0.89 TDP1 (0.55) TDP1KEAP1ALDH1A1FFAR1HDAC2
SCHEMBL1418881 0.88 HDAC1 (0.62) TDP1KEAP1HDAC2HDAC8HDAC6
Hydrochloric Acid SCHEMBL10806350 0.86 HDAC1 (0.60) TDP1KEAP1HDAC2HDAC8HDAC6
SCHEMBL8496248 0.86 MAPT (0.61) TDP1HDAC2HDAC8HDAC6KMT2A
SCHEMBL27287357 0.85 MAPT (0.65) TDP1HDAC2HDAC8HDAC6KMT2A
SCHEMBL1838210 0.84 TDP1 (0.63) TDP1KEAP1ALDH1A1FFAR1HDAC2
SCHEMBL1739439 0.83 TDP1 (0.73) TDP1KEAP1ALDH1A1FFAR1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111909292-B Preparation method and application of O-benzylhydroxylamine resin 国药集团化学试剂有限公司 2022-12-02 CN claimed
CN-111909292-A Preparation method and application of O-benzylhydroxylamine resin 国药集团化学试剂有限公司 2020-11-10 CN claimed
CN-103725239-B A kind of low halogen patch red glue and preparation method thereof YAJU ELECTRONIC MATERIAL CO., LTD. (CN) 2015-09-02 CN claimed
EP-1745022-B1 HISTONE DEACETYLASE INHIBITOR PRODRUGS ATON PHARMA INC (US) 2014-08-13 EP claimed
CN-103725239-A Low-halogen SMT (surface mount technology) adhesive and preparation method thereof DONGGUAN YAJU ELECTRONIC MATERIAL CO LTD 2014-04-16 CN claimed
US-8227636-B2 Histone deacetylase inhibitor prodrugs MERCK HDAC RESEARCH, LLC (US) 2012-07-24 US claimed
CN-102423673-A Latent microcapsule curing agent initiating thermosetting epoxy resin curing at medium temperature and preparation method of adhesive thereof UNIV NORTHWESTERN POLYTECHNIC 2012-04-25 CN claimed
CN-101585929-A Hydrazide latency improving curing agent and preparation method thereof JIAXING RONGTAI LEIPASI INSULA (CN) 2009-11-25 CN claimed
CN-100409324-C Integrated CD/DVD recording and labeling HEWLETT PACKARD DEVELOPMENT CO (US) 2008-08-06 CN claimed
CN-1946567-A Multilayered color-forming compositions and imaging methods HEWLETT PACKARD DEVELOPMENT CO (US) 2007-04-11 CN claimed
CN-1608286-A Integrated CD/DVD recording and labeling HEWLETT PACKARD DEVELOPMENT CO (US) 2005-04-20 CN claimed
WO-1997041798-A1 IMPROVED DENTAL IMPLANT PROCESS AND TREATED PROSTHETIC DEN-MAT CORPORATION (US) 1997-11-13 WO claimed
US-5683249-A Dental implant process and treated prosthetic DEN-MAT CORPORATION (US) 1997-11-04 US claimed
CN-1112125-A Acyloxyhexanoic acid derivatives CIBA GEIGY AG (CH) 1995-11-22 CN claimed
US-12062633-B2 Non-conductive film sheet and semiconductor package including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-08-13 US disclosed
US-11876031-B2 Thermal interface material paste and semiconductor package SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-01-16 US disclosed
CN-111909292-B Preparation method and application of O-benzylhydroxylamine resin 国药集团化学试剂有限公司 2022-12-02 CN disclosed
US-4687873-A Derivatives of β-adrenergic antagonists THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1987-08-18 US disclosed
CN-86100956-A The preparation method of new amides and application 1986-09-10 CN disclosed
EP-0117089-A1 Beta-adrenergic antagonist compounds and derivatives of beta-adrenergic antagonists THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1984-08-29 EP disclosed