SCHEMBL21546065

SCHEMBL21546065

NOC(=O)CCc1ccccc1.[NaH]

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.66
KEAP1 Q14145 1/20 0.57
ALDH1A1 P00352 3/20 0.53
FFAR1 O14842 2/20 0.53
KMT2A Q03164 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
L3MBTL1 Q9Y468 4/20 0.49
MAPT P10636 3/20 0.49
HTT P42858 2/20 0.49
POLB P06746 1/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
HDAC1 Q13547 2/20 0.48
HDAC3 O15379 1/20 0.48
MAPK1 P28482 1/20 0.48
ADRA1A P35348 1/20 0.48
HDAC4 P56524 1/20 0.48
SLC6A3 Q01959 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1811235 0.98 TDP1 (0.68) TDP1KEAP1ALDH1A1FFAR1KMT2A
Hydrochloric Acid SCHEMBL28018100 0.96 TDP1 (0.66) TDP1KEAP1ALDH1A1FFAR1KMT2A
SCHEMBL20815410 0.87 TDP1 (0.55) TDP1KEAP1ALDH1A1FFAR1HDAC2
SCHEMBL15976585 0.87 FFAR1 (0.65) TDP1FFAR1HDAC2HTTHDAC1
SCHEMBL1418881 0.86 HDAC1 (0.62) TDP1KEAP1KMT2AHDAC2HDAC8
Hydrochloric Acid SCHEMBL10806350 0.85 HDAC1 (0.60) TDP1KEAP1KMT2AHDAC2HDAC8
SCHEMBL8496248 0.85 MAPT (0.61) TDP1KMT2AHDAC2HDAC8HDAC6
SCHEMBL27287357 0.83 MAPT (0.65) TDP1KMT2AHDAC2HDAC8HDAC6
SCHEMBL1838210 0.82 TDP1 (0.63) TDP1KEAP1ALDH1A1FFAR1KMT2A
SCHEMBL1739439 0.81 TDP1 (0.73) TDP1KEAP1ALDH1A1FFAR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3792249-B1 PHENYL AMINO SODIUM PROPIONATE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHENZHEN CHIPSCREEN BIOSCIENCES CO LTD (CN) 2025-09-24 EP disclosed
US-11981638-B2 Phenyl amino sodium propionate derivative, preparation method therefor and application thereof SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) 2024-05-14 US disclosed
US-11981638-B2 Phenyl amino sodium propionate derivative, preparation method therefor and application thereof SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) 2024-05-14 US disclosed
US-11981638-B2 Phenyl amino sodium propionate derivative, preparation method therefor and application thereof SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) 2024-05-14 US disclosed
US-20210078948-A1 PHENYL AMINO SODIUM PROPIONATE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) 2021-03-18 US disclosed
US-20210078948-A1 PHENYL AMINO SODIUM PROPIONATE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) 2021-03-18 US disclosed
EP-3792249-A1 PHENYL AMINO SODIUM PROPIONATE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2021-03-17 EP disclosed
EP-3792249-A1 PHENYL AMINO SODIUM PROPIONATE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2021-03-17 EP disclosed
WO-2019214482-A1 PHENYL AMINO SODIUM PROPIONATE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 深圳微芯生物科技股份有限公司 (CN) 2019-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981638-B2 Phenyl amino sodium propionate derivative, preparation method therefor and application thereof SLC6A11, SLC6A13, SLC6A1 TDP1 1688/4885KEAP1 4806/4885ALDH1A1 728/4885
US-20210078948-A1 PHENYL AMINO SODIUM PROPIONATE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SLC6A11, SLC6A13, SLC6A1 TDP1 1688/4885KEAP1 4806/4885ALDH1A1 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.