Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.79 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene Carboxylic Acid SCHEMBL27932787 | 0.91 | DAO (0.86) | DAOCES2CES1HPGDSGSK3B | |
| SCHEMBL1813 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL28208472 | 0.89 | — | — | |
| Thiophene Carboxylic Acid SCHEMBL7062244 | 0.89 | DAO (1.00) | DAOCES2CES1HPGDSGSK3B | |
| Thiophene Carboxylic Acid SCHEMBL27774764 | 0.89 | DAO (1.00) | DAOCES2CES1HPGDSGSK3B | |
| Thiophene Carboxylic Acid SCHEMBL83000 | 0.89 | — | — | |
| Thiophene Carboxylic Acid SCHEMBL5287669 | 0.87 | DAO (0.95) | DAOCES2CES1HPGDSGSK3B | |
| Thiophene Carboxylic Acid SCHEMBL1814 | 0.87 | — | — | |
| Thiophene Carboxylic Acid SCHEMBL20895852 | 0.87 | — | — | |
| Thiophene Carboxylic Acid SCHEMBL11452200 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433242-A1 | PROCESSES FOR THE PREPARATION OF HETEROARYL CARBOXYLIC ACIDS | Monsanto Technology LLC (US) | 2019-01-30 | — | — | EP | disclosed |
| EP-3277275-A1 | PROCESSES FOR THE PREPARATION OF 2-THIOPHENECARBONYL CHLORIDE | Monsanto Technology LLC (US) | 2018-02-07 | — | — | EP | disclosed |
| WO-2017165356-A1 | PROCESSES FOR THE PREPARATION OF HETEROARYL CARBOXYLIC ACIDS | MONSANTO TECHNOLOGY LLC (US) | 2017-09-28 | — | — | WO | disclosed |
| WO-2016161063-A1 | PROCESSES FOR THE PREPARATION OF 2-THIOPHENECARBONYL CHLORIDE | MONSANTO TECHNOLOGY LLC (US) | 2016-10-06 | — | — | WO | disclosed |